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Neuroimaging

Producing images of the structure or activity of the brain and other parts of the nervous system by techniques such as magnetic resonance imaging

What does this
Theme Involve?

The main objectives of this theme include obtaining insights into key pathogenetic mechanisms common to multiple neurological and neuromuscular diseases, stratified to provide benefit to individual patients, and developing and testing imaging biomarkers that will serve as outcome measures to clinical trials in MS, AD, epilepsy, cerebrovascular, neuro-oncology, and neuromuscular diseases. These areas provide unique opportunities for engineers to make a clinical impact on a wide range of pathologies.

Partners and Facilities

The Institute of Neurology at UCL is very active in Neuroimaging research. The wide range of partners we work with include the Multiple Sclerosis NMR Research Unit, Dementia Research Centre, Epilepsy Research Group, Neuroradiological Academic Unit, WTCN, MRC Centre for Neuromucular diseases, Birkbeck-UCL Centre for Neuroimaging and the Centre for Medical Image Computing, all of which are leading centres at UCL.

Being able to take advantage of the many neurological research departments at UCL, facilities are word leading. Examples of this include access to 3 research dedicated Siemens Trio Magnetic resonance imaging (MRI) scanners, D whole-body motion capture system and Illumina HiSeq Next Generation Sequencer.

Studying Under This Theme

Projects listed below are available for applicants to include in their 5 project choices. Successful candidates will meet with both primary supervisors from their selection as part of the induction process before being assigned to an allocated research project. To view all available project videos please visit our YouTube Channel.

Theme Leader

Prof Olga Ciccarelli
UCL Institute of Neurology

Olga Ciccarelli is a Professor Neurology at the Institute of Neurology, University College London (UCL). She is the head of the NMR Research Unit, where a clinical research programme that focuses on the study of multiple sclerosis (MS) using MRI is ongoing. She studied Medicine and Neurology in Rome, Italy. She then obtained a PhD in Neurological Sciences at UCL. In 2004 she was awarded a Wellcome Trust Advanced Clinical Fellowship. In 2014 she became Professor or Neurology.

Her research aims to understand the mechanisms or damage and recovery in the central nervous system in patients with multiple sclerosis (MS). She runs multiple sclerosis specialist and diagnostic clinics, and general neurology clinics. She has more than 110 publications, supervises PhD students and has received grant funding from charities and research council over the years.

She serves as an Associate Editor of Neurology, which is the official journal of the American Academy of Neurology, leading on the neuroimmunology, neurovirology and neuroinfections portfolio.

Available Projects:

Intra and Extracellular Sodium Quantification by Multi-modal Modelling

Machine Learning for Classification and Prognosis of Multiple Sclerosis