Medical imaging is central to the latest advances in the treatment of cardiovascular disease, using innovative research to develop patient-centric therapies
Cardiovascular disease (CVD) is responsible for a third of all deaths nationally and is the major cause of chronic ill health in the UK. Therefore, it is in the national interest to improve outcomes in CVD, and we believe engineering and the physical sciences have a pivotal role to play, in particular with imaging. Cardiovascular imaging at UCL integrates clinicians, magnetic resonance sequence developers, biomedical engineers, and post-processing computer scientists to translate cardiovascular imaging developments from their basic concepts to acceptable use as diagnostics tests in patients. Examples of this rapid translation include the development of novel real-time MR sequences to provide fast MR scans in small children without the need for general anaesthetic; new biomarkers to measure myocardial extracellular volume to provide in-vivo assessment of diffuse myocardial fibrosis and cardiac amyloid; imaging and biomedical engineering modelling techniques to predict patient-specific selection of optimal device treatment.
Using ever more advanced and accurate non-invasive, in-vivo methods allow clinicians to diagnose disease, monitor symptoms and decide on treatment plans. This improves efficacy for patients which in turn reduces trauma, stress and costs. Often, multiple imaging techniques are required to detect the presence and extent of cardiovascular disease. This involves high levels of data which need accurate analysis, taking into account biological factors such as vascular blood flow. This theme is linked to the treatment of cardiovascular disease, both in cases of paediatric or age-related deterioration, which could be heart failure, cardiac amyloid or myocardial fibrosis.
Partners and Facilities
By joining this clinical theme you will develop your research in line with scientists, engineers and clinicians from the Centre for Cardiovascular Imaging, the Institute of Biomedical Engineering, University College Hospital, the Heart Hospital and Great Ormond Street Hospital. You will be working on the latest innovative advancements in imaging techniques and computational modelling to solve front line clinical problems, such as the development of a novel replacement mitral heart valve, or developing computational fluid dynamics to extract the performance or blood flow affected by the narrowing of arteries. You will have access to CT and MRI scanners and the only PET MRI in the country.
Studying Under This Theme
Projects listed below are available for applicants to include in their 5 project choices. Successful candidates will meet with both primary supervisors from their selection before being assigned to their allocated research project to ensure that each student gets the best opportunity for their skills and development. To view all available project videos please visit our YouTube Channel.
Andrew Taylor is Professor of Cardiovascular Imaging at University College London. He is the Head of Cardiovascular Imaging at the UCL Institute of Cardiovascular Science. His main areas of research interest are: the assessment of cardiac physiology using cross-sectional imaging; the development of models of cardiovascular structure, physiology and disease; the development of novel methods to design and assess new cardiovascular devices, the development of image registration methods in cardiovascular imaging; and the assessment of the role of less invasive autopsy in fetuses, neonates and infants.
More about our Clinical Research
- Echocardiography in clinical practice: challenges for training in an expanding field
- Recruitment time for the EPSRC CDT in Medical Imaging
- Two CDT Supervisors winners of the EPSRC Healthcare Technologies Challenge Awards
- Disruptive innovation in paediatric cardiovascular magnetic resonance – the importance of physics and computer science
- Visit us at the UCL Graduate Open Day