Jasper Morrow is a consultant Neurologist at the National Hospital for Neurology and Neurosurgery and also holds an honorary appointment at the MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology. His research involves using Magnetic Resonance Imaging (MRI) in neuromuscular diseases. He applies novel quantitative MRI techniques to nerve and muscle in diseases such as Charcot-Marie-Tooth disease, inclusion body myositis, limb girdle muscular dystrophy, inflammatory neuropathies and periodic paralysis. His research aims in particular to develop MRI not just as a tool for diagnosis in these conditions but also as an outcome measure for future clinical trials and as a tool to guide treatment decisions.
To date he has demonstrated changes in magnetisation transfer ratios of muscle of patients with inherited neuropathies. He has also demonstrated the reliability of three point Dixon (quantitative fat imaging), magnetisation transfer imaging and T1 and T2 mapping in healthy volunteers and are now applying these methods to patient groups. He are correlating MRI data with both isometric and isokinetic muscle strength testing and other clinical measures, and determining the responsiveness of quantitative MRI outcome measures.
Expertise: Molecular Neuroscience