Dr Tachtsidis is a Wellcome Trust Senior Fellow and Reader in Biomedical Engineering. He is a senior member of the Biomedical Optics Research Laboratory and heads the Multi-Modal Spectroscopy Group. His research is highly multi-disciplinary, crossing the boundaries between engineering, physics, neuroscience and clinical medicine. The technical focus of his work is the development and use of non-invasive optical instruments and techniques for monitoring brain oxygenation, haemodynamics and metabolism.
A major part of Dr Tachtsidis’s research is to investigate the use and limitations of functional Near-Infrared Spectroscopy or fNIRS in neuroscience applications. In addition, the clinical focus of his work is the identification and use of optically measured biomarkers to assess the functional status of the brain. The principal challenge of his research is the non-invasive measurement, with NIRS, of cytochrome-c-oxidase (CCO), a mitochondrial enzyme responsible for cellular energy production.
Dr Tachtsidis and his team have developed unique NIRS systems that currently are used at UCL Hospitals in London, to monitor adult traumatic-brain-injury patients and birth asphyxiated infants.