Patient Specific Mitral Valve Modelling
Allocated in academic year 2014-15
The objective of this project is to use engineering methodologies to study and fully characterise the geometrical and dynamic properties of the mitral valve in patients with valve regurgitation using conventional image data. This will facilitate our understanding of the mechanical requirements for a novel transcatheter mitral valve device which could avoid open heart surgery to those patients requiring a new valve. We propose to combine information from the cardiac echo and magnetic resonance imaging studies to create a patient-specific integrated 3D model of the left heart for each individual, combining the complementary information obtained with the different imaging techniques. This computational model will be used to test new devices in a more realistic setting than animal experiments, which in the context of mitral valve regurgitation are not representative of human anatomy and dynamics.