Laparoscopic Cerenkov Luminescence Imaging for Robotic Assisted Urology
Cancer surgeons face a fundamental dilemma between resecting too much tissue and harming the patient or not resecting enough tissue and watching the cancer return soon after the surgery. Lightpoint Medical is developing a molecular imaging camera to analyse tissue in real time during surgery based on Cerenkov Luminescence Imaging (CLI), a ground-breaking imaging modality that can perform optical imaging of Positron Emission Tomography (PET) imaging agents. Lightpoint has completed an initial prototype of the device and in this project we will investigate the adaptation and application of this camera within robotic laparoscopic prostatectomy. A number of computational challenges need to be resolved to achieve this, in particular image alignment when imaging dynamic tissue with long exposure times, removal of signal blur and background illumination noise and compensation of patient specific tissue optical properties. This PhD project will tackle these computational challenges and involve a strong collaboration between engineering (CMIC), surgery (UCLH) and industry (Lightpoint Medical).
Full Team involved
Technical team: Dr. Danail Stoyanov, Prof. Simon Arridge
Clinical team: Prof. John Kelly, Dr. Paul Cathcart, Dr. Ashwin Sridhar