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21 Sep

Development of non-invasive MRI methods to measure cerebral blood flow for early detection of dementia

by Dr David Thomas
Allocated Projects

Project Allocated in 2016-17 Arterial spin labelling (ASL) is a non-invasive, contrast-free MRI method for the measurement of cerebral blood flow (CBF). It is able to provide quantitative whole-brain CBF maps in scan times of a few minutes. ...

21 Sep

Multi-Scale Multi-Modal Retinal Image Fusion: From Neurons to Vessels

by Dr. Christos Bergeles
Allocated Projects

Project allocated in 2016-2017 Adaptive Optics (AO) is an optical imaging method that enables the observation of individual photoreceptor cells in the eye. With such micrometre level observations, clinicians can evaluate the condition of the...

21 Sep

Optimising MRI Susceptibility Mapping Methods to Investigate the Effects of Sickle Cell Anaemia on Iron Levels in the Brains of Young Patients

by Dr Karin Shmueli
Allocated Projects

Project Allocated in 2016-2017 Sickle cell anaemia (SCA) is a single-gene disorder that affects haemoglobin, causing red blood cells (RBCs) to become abnormal, fragile and ‘sickle’-shaped. SCA affects 1 in 2000 UK births and as many as 1 in ...

13 Sep

Clinical role of MRS quantification of 2HG in diagnosis of malignant gliomas and assessment of therapy response

by Ms Rebecca Holmes
Allocated Projects

Project Allocated in 2016-2017 The evaluation of glioma therapies relies on quantifying response rates. Gliomas with mutant IDH (isocitrate dehydrogenase) present a metabolic alteration resulting in overproduction of the oncometabolite 2-hyd...

13 Sep

Photoacoustic imaging of head and neck cancer

by Prof. Paul Beard
Allocated Projects

Allocated in Academic Year 2016-2017 Lymph nodes are a foremost site of metastasis in many cancers and establishing their level of involvement is important for disease staging, prognosis and treatment planning. Extranodal spread – breaching ...

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