Imaging of the Placenta for Fetal Surgery
UCL was recently awarded £10 million to develop tools and imaging techniques that will improve the success of surgery and other therapies on unborn babies. This research will be performed in collaboration with KU Leuven, Great Ormond Street Hospital and University College London Hospital.
During fetal surgery, it is critical to accurately visualise and characterise vasculature of the placenta. Fetoscopic imaging of the uterus currently provides very limited information about hemodynamic variations and oxygenation.
This PhD project will involve the development of new methods for significantly extending our ability to obtain quantitative information from fetoscopic images. These developments will have hardware components, such as optics and electronics to acquire multispectral images, and software components, such as time series analysis and overlay of physiological parameters onto video streams in real-time. Studies will be performed with patient data as well as laboratory mock-ups. The results could set the stage for a wide range of new therapeutic interventions in pregnancy and other clinical areas.