Clinical Seminar: Paediatric Imaging & Stem Cells
As an investigator from the GIFT-Surg Project, Paolo has a special interest in congenital malformations and their treatment using minimally invasive techniques. He has focused his research interests on stem cells and tissue engineering, trying to find new modalities for the treatment of complex congenital anomalies. While working with Dr A. Atala at the Childrens’ Hospital in Boston-US, he had the opportunity of identifying a new source of cells for therapeutic applications, showing the possibility of using stem cells from amniotic fluid. More recently, his team has demonstrated that these cells are able to differentiate into various tissues and to replace functional activity in animal models of diseases. He is now focused on developing reliable methods for stem cell isolation, expansion and differentiation at clinical level (GMP-grade). In 2010 he was part of the team, which performed the first successful transplantation of a tissue-engineered trachea on a child at the Great Ormond Street Hospital. Hear about the research history and how it can be applied using minimally invasive techniques which require new imaging techniques to achieve.
Paolo De Coppi is the Professor of Paediatric Surgery and Head of Stem Cells and Regenerative Medicine Section, Developmental Biology & Cancer Programme at the UCL Institute of Child Health. He is also NIHR Professor and Consultant Paediatric Surgeon at the Great Ormond Street Hospital for Children and the UCL Institute of Child Health. Paolo is also the newly announced Clinical Theme Leader for Paediatric Imaging for the Centre for Doctoral Training in Medical Imaging and an investigator on the GIFT-Surg Project.
Find out more about GIFT-Surg